ABOUT
I am Dana Lorber, and I study mechanobiology processes in vivo,
in a live intact organism, specifically in skeletal muscles.
After receiving my PhD from the Technion, Israel Institute of Technology in biomedical engineering, I worked in the bio-tech industry in research, development, and management positions.
I later held an academic appointment at an engineering college in Israel in the faculty of Mechanical and Biomedical Engineering.
While I was a lecturer, I initiated my research at the Weizmann Institute of Science.
Currently, I am a research associate at the Weizmann Institute of Science, Israel.
To study muscle mechanotransduction, we developed a device to explore cellular and nuclear
mechanotransduction on the molecular and tissue levels in live, intact models. Combining microscopy, quantitative image analysis, and genetic tools, reveals the spatiotemporal dynamics of the players involved in mechanotransduction pathways, whether mechanical or chemical.
See this talk I gave as part of the
INC consortium for an overview of my
research approach.
Read this post from FocalPane
describing the development of the device
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New findings require new analysis tools.
To quantify 3D radial chromatin distribution in the nucleus we teamed up with Arivis to develop the matryoshka analysis Click the image for more details and a tutorial
